Cell· Xiao Zhang, Guangyao Lai, Xiangyu Guo, Wen Ma, Yue Yuan, Han Zhang, Bo Zhang, Peng Fan, Xingyuan Liu, Pengcheng Guo, Juan An, Jinxiu Li, Keke Huang, Xiaoyan Li, Jing Zuo, Liang Wu, Shuncheng Shangguan, Feng Yu, Yuchen Xiang, Yuebei Hu, Yuxuan Liu, Yunting Huang, Yiting Lin, Dajian He, Mingtian Pan, Laiqiang Chen, Bang Li, Jiawei Zhang, Qintian Guo, Weili Yang, Peng Yin, Shihua Li, Xiaolan Zhang, Tao Yang, Xiaofeng Wei, Yuan Lv, Baoming Qin, Xiaobing Qing, Qiuting Deng, Yaling Huang, Chang Liu, Lei Han, Shiping Liu, Dajiang Qin, Zhen Liu, Yi Zhou, Liang Qiao, Chengyu Li, Yanxiao Zhang, Zunpeng Liu, Yan Li, Paulina Carriba, Mara Dierssen, Giacomo Volpe, Simon Graf, Ian Ferenc Diks, Matthias Flotho, Rafal P. Krol, Jan Mulder, Chaiyaboot Ariyachet, Nattiya Hirankarn, Andrew P. Hutchins, Andreas Keller, Patrick H. Maxwell, David C. Rubinsztein, Pura Muñoz-Cánoves, Xiaolei Liu, Hung-Fat Tse, Muming Poo, Bo Wang, Longqi Liu, Ying Gu, Jun Xie, Xun Xu, Xiaojiang Li, Chuanyu Liu, Yiwei Lai, Miguel A. Esteban, Mingyuan Liu·精选AI 评分78
跨成年猕猴一生的多模态脑细胞图谱
Multimodal brain cell atlas across the adult macaque lifespan
AI 导读
研究构建了覆盖成年猕猴一生的多模态单核图谱，包含8个脑区、2,955,873个细胞核，并纳入极为高龄的个体。图谱揭示了衰老过程中脑区特异的与共有的细胞易感性模式，为解析灵长类脑老化、长寿与神经退行性变背后的共享及分化分子程序提供框架。
推荐理由
该图谱覆盖成年猕猴一生八个脑区、近300万细胞核，为比较脑老化的区域易感性与保守分子程序提供参照。
来源：Cell · cell.com